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Semaglutide Dose & Titration Calculator (Canada)

5 mg vial + 2 mL water = 2.50 mg/mL → a 250 mcg dose draws to 10 units (0.10 mL).

Typical dose
250 mcg
Frequency
1× weekly
Half-life
~7 days
Route
Subcutaneous, weekly
Draw to
10.0 units
050100 units
Draw to the red line
Concentration
2.50 mg/mL
Draw volume
0.100 mL
Doses per vial
20
Typical frequency: 1× weekly
Note: Titrate every 4 wks: 0.25→0.5→1.0→1.7→2.4 mg.
Research use only

Outputs are a reference for research-protocol design and reflect ranges published in peer-reviewed and rodent-model literature. Not medical advice, not a prescription. Compounds are sold for laboratory research use only.

Open the GLP-1 titration planner →

Frequently asked questions

How do I reconstitute Semaglutide?

Add bacteriostatic water down the wall of the lyophilized vial and swirl gently. A 5 mg vial with 2 mL yields 2.50 mg/mL.

How many units do I draw for Semaglutide?

At 2.50 mg/mL, a 250 mcg dose draws to about 10 units on a U-100 syringe. Adjust the water in the calculator to change the concentration.

What is a typical Semaglutide dose?

A common research dose is 250 mcg per administration. Use the calculator with your vial size and water volume to get the exact draw.

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